Dr Scott McCue applied mathematics from the University of Queensland technology, who led the research said, "Our idea is to build a mathematical model to simulate first, then apply to the method specific treatment of wounds"
Skin has two layers of cells that are important to the treatment of wounds. Epidermis concentrated a lot of keratinocytes, while below the dermis has more hair cells. During the recovery process of the wound, these cells interact through the growth factor and a similar adhesive glue. When wound healing, these cells proliferate and fill the damaged area. The simulation shows us clearly that the process of filling.
This is the first simulation program fully reflect the complex interactions involved in skin wounds recover. The team has collected biological data to serve for the construction of this model. The data include the proportion of different cell types in the skin, the concentration of growth factors, and the amount of binder in the recovery phase of various wounds and normal wounds with signs abnormalities.
After many trials, this model can simulate successfully wound recovery process normally and the process leads to chronic wounds or scars. This result can be used for reference during the actual treatment, helps physicians to clearly visualize a recovery process for the user to adjust the maximum to prevent scarring. According to Dr. Scott, as early treatment, wound as a low risk of scarring. The above model also provides the optimal period is 2-5 days after the injury occurs. Ultimate motto is "As soon as possible".
Since this is one of the few complex models to date so of course it's still a limited number are being improved. This is only a 2D model based on wound size rectangle equivalent to a real wound round a diameter of about 10mm. The team is still trying to complete the upgrade it into a 3D model and reflect the many different shapes wound with larger size. |